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All India Institute of Medical Sciences, Nagpur
All India Institute of Medical Sciences, Nagpur

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Clinical Heamatology Research and Publications

Details of Research

  • Funded Project

Duration: January 2024 to December 2024 (Excluding Clinical Trials)

Sr. No.

Title of Project

Proposal No. (IEC No.)

Name of Principle Investigator

Amount of Grant Received

Name of Funding Agency

Collaboration  with other

 institute (if any)

Status of Project (Ongoing/ Completed)

Publication (YES/NO)

1

ICMR ISCALL: ICiCLE Implementation study IEC/PHARMAC/2023/710 Dr. Vishvdeep Khushoo Rs. 3,311,378.2 ICMR Hub Spoke Model Study Ongoing NO

2

A multicenter, open -label, randomized, phase III clinical trail to evaluate efficacy and safety, PF-114 versue imatinib at 600 or 800 mg daily in adult patients with Philadelphia chromosome positive (ph+) CML IN CP resistance to imatinib at daily doses of 400 or 600mg.



Dr. Vishvdeep Khushoo   cliantha   Ongoing NO

3

A Phase 1, Open Label, Dose Escalation, Dose Expansion, Multicenter Study Evaluating Safety, Pharmacokinetics and Pharmacodynamics of Oral AUR108 in Patients with Relapsed Advanced Lymphoma (ASHA 1) ECCT/PHARMAC/2023/355 Dr. Vishvdeep Khushoo Rs. 4,20,125 Cliantha NA Ongoing NO
  • Clinical Trials

Sr. No. 

Title of Project

Clinical Trial No.

Name of Principle Investigator

Amount Received

Sponsors

Status of Project (Ongoing/ Completed)

Publication (YES/NO)

1

ICMR ISCALL: ICiCLE Implementation study

IEC/PHARMAC/2023/710

Dr. Vishvdeep Khushoo

Rs. 3,311,378.2

ICMR

Ongoing

No

2

A multicenter, open -label, randomized, phase III clinical trial to evaluate efficacy and safety, PF-114 versue imatinib at 600 or 800 mg daily in adult patients with Philadelphia chromosome positive (ph+) CML IN CP resistance to imatinib at daily doses of 400 or 600mg.   Dr. Vishvdeep Khushoo   Cliantha

Ongoing

No

3

Phase 1, Open Label, Dose Escalation, Dose Expansion, Multicenter Study Evaluating Safety, Pharmacokinetics and Pharmacodynamics of Oral AUR108 in Patients with Relapsed Advanced Lymphoma (ASHA 1) ECCT/PHARMAC/2023/355 Dr. Vishvdeep Khushoo Rs. 4,20,125 Cliantha

Ongoing

No

  • Undergraduates/Postgraduates/PhD Research

1.Evaluation of effect of hydroxyurea treatment on inflammatory and oxidative stress markers among adults with Sickle cell disease
2.Comparision of LILRA3 levels between patients with thrombotic and non-thrombotic APLA syndrome
3.Study of association between lymphocyte subset analysis in bone marrow at diagnosis and risk category and post treatment response assessment in cases of acute leukemia- a prospective observational study

Publications

DR. SANTOSH RATHOD
1.Khan AA, Rathod SG.Hereditary Dehydrated Stomatocytosis due to PIEZO1 Mutation and Potential Therapeutic Target for Sickle Cell AnaemiaJ Clin of Diagn Res.2025; 19(7):GL01-GL02.
2.Rathod, S. G., Kabir, S., Geelani, S. A., Khan, A. A., Roshan, R., & Bhat, J. R. (2025). Congenital Methemoglobinemia: A Cause of Polycythemia. Indian journal of pediatrics, 92(4), 431
3.Rathod SG, Sakthivel V, Vane A, Kabir S, Khushoo VK. Fatal intracranial bleedings in a viper bite. Chin J Traumatol. Published online July 21, 2025.
4.Sabharwal D, Rathod SG. Local envenomation by green pit viper complicated with airway obstruction. Turk J Emerg Med. 2025 Jul 1;25(3):250. doi: 10.4103/tjem.tjem_110_25. PMID: 40746571; PMCID: PMC12309814.
5.Rathod SG, Kabir S, Kandi K. Floor Bed, Acute Abdomen, and Descending Paralysis: A Clinical Presentation of Krait Bite. J Pharm Bioallied Sci. 2025 Sep;17(Suppl 3):S2846. doi: 10.4103/jpbs.jpbs_1020_25. Epub 2025 Sep 20. PMID: 41164699; PMCID: PMC12563983.

DR. VISHVDEEP KHUSHOO
1. Mehta, D. M.P., Khushoo, V. Is Old (Fludrabine/Busulfan/CyclophosphamideltAntiThymocyte Conditioning StillGold for Allogeneic Transplants in Transfusion Dependent Beta-Thalassemia of AllRisk Categories in 21st Century? Indian J Hematol Blood Transfus 39, 615-623 (2023). https:/doi.org/10.1007s12288-023 01646-1 Globulin)
2. Mehta, Pallavi & Khushoo, Vishvdeep. (2023). Haploidentical Stem Cell Transplantation for Hematological Disorders: Real-World Experience from India. South Asian Journal of Cancer. 10.1055/s-0043-1771274.
Mirgh S, Sharma A, Shaikh MRMA, Kadian K, Agrawal N, Khushoo V, Mehta P, Ahmed R, Bhurani D. Hypomethylating agents+venetoclax induction therapy in acute myeloid leukemia unfit for intensive chemotherapy - novel avenues for lesser venetoclax duration and patients with baseline infections from a developing country. Am JBlood Res. 2021 Jun 15;11(3):290-302. PMID: 34322294: PMCID: PMC8303019.
3. Jadhav, S., Naik, M., Ojha, N.,Sahoo, T., Panchal, A., et,al. (2024). Application of Optical Genome Mapping to the Risk Stratification and Treatment Optimization of Hematologic Diseases. AdvHema Onco Res, 7(2), 01-10.
4. Yadav, Neha'; Mirgh, Sumeet P.123, Aggarwal, Mukul'; Agrawal,Narendra';Mehta, Pallavi'; Khushoo, Vishvdeep'; Kapoor, Jyotsna';Bhatia,Niharika'; Agrawal, Pragya'; Ahmed, Rayaz'; Bhurani, Dinesh. Secondstemcell transplantation for treatment of relapsed/refractory multiple myeloma after first autologous stem celltransplant: A15-year retrospective institutional analysis. Indian Journal of Cancer 60(3): p 316-324, Jul-Sep 2023.DOl: 10.4103/jc.IJC_272_21
5. Sab, Pinjari Chinigi; Khushoo, Vishvdeep2; Erythrocytapheresis in a sickle cell disease patient with a thalamic space-occupying lesion. Asian Journal of Transfusion Science ():10.4103/ajts.ajts_58_24, July 22, 2025. | DOI: 10.4103/ajts.ajts_58_24
6. Khushoo V, Gade N, Pandoraea pnomenusa Bacteremia in an Acute Myeloid Leukaemia Patient: A Rare and Emerging Pathogen. Clin Case Rep Open Access. 2025;8(2):335.
7. Singh S, Choudhary S, Srivastava A, Prakashey AR, Khushoo V. Hereditary haemorrhagic telangiectasia in skin of colour: a dermoscopic, histopathological and radiological approach. BMJ Case Rep. 2025 May 28;18(5):e265940. doi: 10.1136/bcr-2025-265940. PMID: 40441746.